CALCOCO1 antibody

Catalog No. ABIN7246682

Product Details anti-CALCOCO1 Antibody

Target: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CALCOCO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human CALCOCO1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CALCOCO1

Target: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Alternative Name: CALCOCO1 (CALCOCO1 Products)

Synonyms: Cocoa antibody, calphoglin antibody, fa11a10 antibody, wu:fa11a10 antibody, CALCOCO1 antibody, Xdsg antibody, cocoa antibody, dsgc antibody, pp13275 antibody, 1810009B06Rik antibody, Gcap11 antibody, mKIAA1536 antibody, calcium binding and coiled-coil domain 1 antibody, calcium binding and coiled-coil domain 1a antibody, calcium binding and coiled-coil domain 1 S homeolog antibody, calcium binding and coiled-coil domain 1 L homeolog antibody, calcium binding and coiled coil domain 1 antibody, CALCOCO1 antibody, calcoco1a antibody, calcoco1.S antibody, calcoco1.L antibody, Calcoco1 antibody

Background: CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 77 kDa

UniProt: Q9P1Z2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding