SCRN2 antibody

Catalog No. ABIN7246619

Product Details anti-SCRN2 Antibody

Target: SCRN2 (Secernin 2 (SCRN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCRN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human SCRN2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.08 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SCRN2

Target: SCRN2 (Secernin 2 (SCRN2))

Alternative Name: SCRN2 (SCRN2 Products)

Synonyms: MGC147610 antibody, si:ch211-184m19.2 antibody, Ses2 antibody, AV001119 antibody, D11Moh48 antibody, SES2 antibody, secernin 2 antibody, secernin 2 S homeolog antibody, SCRN2 antibody, scrn2 antibody, scrn2.S antibody, Scrn2 antibody

Background: The SCRN (Secernin) gene family has three vertebrate paralogs, i.e. SCRN1, SCRN2 and SCRN3, which are closely linked to human HOXA, HOXB and HOXD cluster, respectively. SCRN2 (secernin-2) is a 425 amino acid protein that belongs to the peptidase C69 family and the Secernin subfamily. Vertebrate SCRN genes showed a topology of the form (A)(BC), i.e. (Hsa2 Hsa7)(Hsa17), with SCRN2 falling outside the SCRN3-SCRN1 cluster. The SCRN2 gene is conserved in dog, cow, mouse, rat and zebrafish, and maps to human chromosome 17q21.32. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Chromosome 17 is linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 47 kDa

UniProt: Q96FV2