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LSM10 antibody

LSM10 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7246445
  • Target See all LSM10 Antibodies
    LSM10 (LSM10, U7 Small Nuclear RNA Associated (LSM10))
    Reactivity
    • 17
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 14
    • 3
    Rabbit
    Clonality
    • 14
    • 3
    Polyclonal
    Conjugate
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LSM10 antibody is un-conjugated
    Application
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human LSM10
    Isotype
    IgG
    Top Product
    Discover our top product LSM10 Primary Antibody
  • Application Notes
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LSM10 (LSM10, U7 Small Nuclear RNA Associated (LSM10))
    Alternative Name
    LSM10 (LSM10 Products)
    Synonyms
    MST074 antibody, MSTP074 antibody, LSM10, U7 small nuclear RNA associated antibody, U7 snRNP-specific Sm-like protein LSM10 antibody, LSM10 antibody, lsm10 antibody, Lsm10 antibody
    Background
    LSm10 (U7 snRNA-associated Sm-like protein LSm10) is a nuclear protein that belongs to the snRNP (small nuclear ribonucleoproteins) Sm protein family. The survival of motor neurons (SMN) complex mediates the assembly of snRNPs involved in splicing and histone RNA processing. A crucial step in this process is the binding of Sm proteins onto the SMN protein. LSm10 and LSm11, mammalian homologs of the yeast Sm proteins D1 and D2, are important for U7 snRNP function and subcellular localization. U7 snRNP is an RNA molecule involved in the splicing of animal histone pre-mRNAs. Lsm10 and Lsm11 also associate with pICln (Chloride ion current inducer protein), which interacts with Sm proteins to inhibit their assembly on U RNA. LSm10 interactions with U7 snRNA and pICln may provide the means for using modified U7 snRNA derivatives to alter specific pre-mRNA splicing events, potentially leading to advances in antisense gene therapy.
    UniProt
    Q969L4
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