Thimet Oligopeptidase 1 antibody

Catalog No. ABIN7246397

Product Details anti-Thimet Oligopeptidase 1 Antibody

Target: Thimet Oligopeptidase 1 (THOP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human THOP1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: THOP1 (THOP1 Products)

Synonyms: EP24.15 antibody, MEPD_HUMAN antibody, MP78 antibody, TOP antibody, AI131655 antibody, AI327041 antibody, THOP1 antibody, thop1 antibody, MGC147297 antibody, LOC397806 antibody, mepd antibody, thimet oligopeptidase 1 antibody, thimet oligopeptidase 1 L homeolog antibody, thimet oligopeptidase antibody, peptidase antibody, Thimet oligopeptidase antibody, THOP1 antibody, Thop1 antibody, thop1 antibody, thop1.L antibody, Tc00.1047053506411.10 antibody, Tc00.1047053511237.10 antibody, Noca_4613 antibody, ANI_1_1400064 antibody, MBOO_RS10705 antibody, AOR_1_880174 antibody, AnaeK_0425 antibody, MPAL_RS03920 antibody, Hoch_5061 antibody, mepd antibody

Background: The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 79 kDa

UniProt: P52888