DENND1B antibody
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- Target See all DENND1B Antibodies
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DENND1B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Fusion protein of human DENND1B
- Isotype
- IgG
- Top Product
- Discover our top product DENND1B Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.54 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
- Alternative Name
- DENND1B (DENND1B Products)
- Background
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.
- Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 86 kDa
- UniProt
- Q6P3S1
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