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DENND1B antibody

DENND1B Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7246211
  • Target See all DENND1B Antibodies
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Reactivity
    • 31
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 45
    • 1
    Rabbit
    Clonality
    • 46
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DENND1B antibody is un-conjugated
    Application
    • 39
    • 15
    • 15
    • 14
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human DENND1B
    Isotype
    IgG
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    Discover our top product DENND1B Primary Antibody
  • Application Notes
    WB 1:500-1:2000, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.54 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Alternative Name
    DENND1B (DENND1B Products)
    Synonyms
    C1ORF18 antibody, C1orf218 antibody, FAM31B antibody, 4632404N19Rik antibody, 4930467M19Rik antibody, 6820401H01Rik antibody, F730008N07Rik antibody, Fam31b antibody, si:ch211-195i21.1 antibody, DENN domain containing 1B antibody, DENN/MADD domain containing 1B antibody, DENND1B antibody, dennd1b antibody, Dennd1b antibody
    Background
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 86 kDa

    UniProt
    Q6P3S1
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