Chordin antibody

Catalog No. ABIN7246175

Product Details anti-Chordin Antibody

Target: Chordin (CHRD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chordin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human CHRD

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Chordin

Target: Chordin (CHRD)

Alternative Name: CHRD (CHRD Products)

Synonyms: chd antibody, X-chordin antibody, Chd antibody, chordino antibody, wu:fe47d04 antibody, chordin antibody, chordin, gene 1 antibody, chordin, gene 1 S homeolog antibody, CHRD antibody, chrd.1 antibody, LOC778563 antibody, Chrd antibody, chrd antibody, chrd.1.S antibody

Background: CHRD (Chordin) is a Protein Coding gene. Diseases associated with CHRD include Cornelia De Lange Syndrome. Among its related pathways are Mesodermal Commitment Pathway and TGF-beta signaling pathway (KEGG). GO annotations related to this gene include heparin binding and syndecan binding. An important paralog of this gene is CHRDL2.This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined.

UniProt: Q9H2X0