EEF1E1 antibody

Catalog No. ABIN7245833

Product Details anti-EEF1E1 Antibody

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEF1E1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Alternative Name: EEF1E1 (EEF1E1 Products)

Synonyms: p18 antibody, AIMP3 antibody, P18 antibody, 1110003A02Rik antibody, eukaryotic translation elongation factor 1 epsilon 1 antibody, eukaryotic translation elongation factor 1 epsilon 1 L homeolog antibody, EEF1E1 antibody, eef1e1.L antibody, eef1e1 antibody, Eef1e1 antibody

Background: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 20 kDa

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus