KCTD16 antibody

Catalog No. ABIN7245797

Product Details anti-KCTD16 Antibody

Target: KCTD16 (Potassium Channel Tetramerisation Domain Containing 16 (KCTD16))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human KCTD16

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KCTD16

Target: KCTD16 (Potassium Channel Tetramerisation Domain Containing 16 (KCTD16))

Alternative Name: KCTD16 (KCTD16 Products)

Synonyms: RGD1559856 antibody, 4930434H12Rik antibody, Gm1267 antibody, lrl1 antibody, lrl3 antibody, potassium channel tetramerization domain containing 16 antibody, potassium channel tetramerisation domain containing 16 antibody, potassium channel tetramerization domain containing 16a antibody, potassium channel tetramerization domain containing 16b antibody, Kctd16 antibody, KCTD16 antibody, kctd16 antibody, kctd16a antibody, kctd16b antibody

Background: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 49 kDa

UniProt: Q68DU8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling