EARS2 antibody

Catalog No. ABIN7245506

Product Details anti-EARS2 Antibody

Target: EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EARS2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human EARS2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EARS2

Target: EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))

Alternative Name: EARS2 (EARS2 Products)

Synonyms: mse1 antibody, 3230401I01Rik antibody, AL024049 antibody, mKIAA1970 antibody, COXPD12 antibody, MSE1 antibody, RGD1307904 antibody, ears2 antibody, glutamyl-tRNA synthetase 2, mitochondrial antibody, zgc:153247 antibody, EARS2 antibody, ears2 antibody, Ears2 antibody, zgc:153247 antibody

Background: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.

UniProt: Q5JPH6