SIX Homeobox 6 antibody

Catalog No. ABIN7003647

Product Details anti-SIX Homeobox 6 Antibody

Target: SIX Homeobox 6 (SIX6)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIX Homeobox 6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human SIX6

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SIX Homeobox 6

Target: SIX Homeobox 6 (SIX6)

Alternative Name: SIX6 (SIX6 Products)

Synonyms: MCOPCT2 antibody, OPTX2 antibody, Six9 antibody, Optx2 antibody, Six6 antibody, MGC63871 antibody, zgc:63871 antibody, Six6.1 antibody, Six6.2 antibody, XOptx2 antibody, optx2 antibody, xSix6 antibody, si:dkey-225h23.3 antibody, zgc:110344 antibody, SIX homeobox 6 antibody, sine oculis-related homeobox 6 antibody, SIX homeobox 6a antibody, SIX homeobox 6 L homeolog antibody, SIX homeobox 6b antibody, SIX6 antibody, Six6 antibody, six6a antibody, six6.L antibody, six6b antibody

Background: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).SIX6 (SIX Homeobox 6) is a Protein Coding gene. Diseases associated with SIX6 include Optic Disc Anomalies With Retinal And/Or Macular Dystrophy and Six6-Related Eye Disorders. Among its related pathways are Ectoderm Differentiation. GO annotations related to this gene include transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is SIX3.

UniProt: O95475