SCDO4 antibody, bHLHb37 antibody, hes family bHLH transcription factor 7 antibody, hairy and enhancer of split 7 (Drosophila) antibody, HES7 antibody, Hes7 antibody
Background
This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.