Fbx45 antibody, 2610017J04Rik antibody, AI463119 antibody, BC026799 antibody, zgc:65875 antibody, 3g27 antibody, F-box protein 45 antibody, F-box protein 45 S homeolog antibody, FBXO45 antibody, fbxo45 antibody, Fbxo45 antibody, fbxo45.S antibody
Background
Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).