ETAA1 antibody

Catalog No. ABIN7244876

Product Details anti-ETAA1 Antibody

Target: ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETAA1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human ETAA1

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ETAA1

Target: ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))

Alternative Name: ETAA1 (ETAA1 Products)

Synonyms: ETAA16 antibody, ETAA1 antibody, 5730466H23Rik antibody, AA672646 antibody, etaa1 antibody, MGC145507 antibody, MGC81344 antibody, RGD1560957 antibody, zgc:171518 antibody, ETAA1, ATR kinase activator antibody, Ewing tumor-associated antigen 1 antibody, Ewing tumor associated antigen 1 antibody, ETAA1, ATR kinase activator L homeolog antibody, ETAA1 antibody, Etaa1 antibody, etaa1 antibody, etaa1.L antibody

Background: ETAA1 (Ewing's tumor-associated antigen 1), also known as ETAA16, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA1 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstrom syndrome.

UniProt: Q9NY74