SLC25A27 antibody

Catalog No. ABIN7244864

Product Details anti-SLC25A27 Antibody

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A27 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human SLC25A27

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC25A27

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Alternative Name: SLC25A27 (SLC25A27 Products)

Synonyms: UCP4 antibody, Ucp4 antibody, 3632410G24Rik antibody, 9430092A03Rik antibody, D530043E16Rik antibody, solute carrier family 25 member 27 antibody, solute carrier family 25, member 27 antibody, SLC25A27 antibody, Slc25a27 antibody

Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 36 kDa

UniProt: O95847