MED23 antibody

Catalog No. ABIN7003463

Product Details anti-MED23 Antibody

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED23 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human MED23

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MED23

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Alternative Name: MED23 (MED23 Products)

Synonyms: CG3695 antibody, Dmel\\CG3695 antibody, Gal11/SUR2 antibody, Med23 antibody, Trap150 antibody, Trap150beta antibody, dSUR2 antibody, dTRAP150beta antibody, CRSP3 antibody, MED23 antibody, ARC130 antibody, CRSP130 antibody, CRSP133 antibody, DRIP130 antibody, MRT18 antibody, SUR-2 antibody, SUR2 antibody, 130kDa antibody, 3000002A17Rik antibody, Crsp3 antibody, ESTM7 antibody, Sur2 antibody, X83317 antibody, mKIAA1216 antibody, crsp3 antibody, si:ch211-272f15.2 antibody, zgc:91979 antibody, Mediator complex subunit 23 antibody, mediator complex subunit 23 antibody, mediator of RNA polymerase II transcription subunit 23 antibody, mediator complex subunit 23 L homeolog antibody, Mediator of RNA polymerase II transcription subunit 23 antibody, MED23 antibody, med23 antibody, LOC412332 antibody, Med23 antibody, med23.L antibody, sur-2 antibody

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q9ULK4

Pathways: Regulation of Lipid Metabolism by PPARalpha