ARIH1 antibody
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- Target See all ARIH1 Antibodies
- ARIH1 (Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARIH1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human ARIH1
- Isotype
- IgG
- Top Product
- Discover our top product ARIH1 Primary Antibody
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anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibody
Verified ARIH1 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibodyARIH1 Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Rat, Bat, Chicken, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibodyARIH1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) antibodyARIH1 Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibodyARIH1 Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) antibodyARIH1 Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio) WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:100, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ARIH1 (Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1))
- Alternative Name
- ARIH1 (ARIH1 Products)
- Background
- ARIH1 (ariadne homolog), also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI (human homolog of Drosophila ariadne), MOP-6 (monocyte protein 6) or UBCH7BP (UBCH7 binding protein), is a 557 amino acid cytoplasmic protein. Expressed in a wide variety of tissues, ARIH1 contains two RING-type zinc fingers and one IBR (in-between RING fingers)-type domain. ARIH1 is believed to be involved in protein degradation and protein translation. ARIH1 interacts with UBCH7 and is thought to function as an E3 ubiquitin-protein ligase (or as a component of an E3 complex) that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme (UBCH7) and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, ARIH1 interacts with and polyubiquitylates eIF4E2, thereby targeting it for proteasomal degradation.
- UniProt
- Q9Y4X5
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