CDC20B antibody

Catalog No. ABIN7003416

Product Details anti-CDC20B Antibody

Target: CDC20B (Cell Division Cycle 20B (CDC20B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC20B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human CDC20B

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDC20B

Target: CDC20B (Cell Division Cycle 20B (CDC20B))

Alternative Name: CDC20B (CDC20B Products)

Synonyms: EG238896 antibody, EG622422 antibody, cell division cycle 20B antibody, CDC20B antibody, Cdc20b antibody

Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Cdc20B (cell division cycle 20 homolog B) is a 519 amino acid protein that contains seven WD repeats and is thought to play a role in cell cycle control. Multiple isoforms of Cdc20B exist due to alternative splicing events. The gene encoding Cdc20B maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

UniProt: Q86Y33