LRRC16A antibody

Catalog No. ABIN7244636

Product Details anti-LRRC16A Antibody

Target: LRRC16A (Leucine Rich Repeat Containing 16A (LRRC16A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC16A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human LRRC16A

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LRRC16A

Target: LRRC16A (Leucine Rich Repeat Containing 16A (LRRC16A))

Alternative Name: LRRC16A (LRRC16A Products)

Synonyms: CARMIL antibody, CARMIL1 antibody, CARMIL1a antibody, LRRC16 antibody, dJ501N12.1 antibody, dJ501N12.5 antibody, 1110037D04Rik antibody, AI425970 antibody, D130057M20 antibody, Lrrc16 antibody, capping protein regulator and myosin 1 linker 1 antibody, CARMIL1 antibody, Carmil1 antibody

Background: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).

UniProt: Q5VZK9