MOSC1 antibody

Catalog No. ABIN7244549

Product Details anti-MOSC1 Antibody

Target: MOSC1 (MOCO Sulphurase C-terminal Domain Containing 1 (MOSC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOSC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human MARC1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MOSC1

Target: MOSC1 (MOCO Sulphurase C-terminal Domain Containing 1 (MOSC1))

Alternative Name: MARC1 (MOSC1 Products)

Synonyms: MOSC1 antibody, 1300013F15Rik antibody, Mosc1 antibody, mosc1 antibody, mosc2 antibody, sb:cb792 antibody, mitochondrial amidoxime reducing component 1 antibody, mitochondrial amidoxime reducing component 1 S homeolog antibody, zgc:110783 antibody, MARC1 antibody, Marc1 antibody, marc1.S antibody, zgc:110783 antibody

Background: MOSC1 (MOCO sulphurase C-terminal domain containing 1), also known as MARC1, is a 337 amino acid mitochondrial protein that is thought to function as an oxidoreductase. Existing as three alternatively spliced isoforms, MOSC1 contains one MOSC domain and binds molybdenum as a cofactor. The gene encoding MOSC1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

NCBI Accession: NP_073583

UniProt: Q5VT66

Pathways: SARS-CoV-2 Protein Interactome