VPS4A antibody

Catalog No. ABIN7244423

Product Details anti-VPS4A Antibody

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS4A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human VPS4A

Isotype: IgG

Application Details

Application Notes: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VPS4A

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Alternative Name: VPS4A (VPS4A Products)

Synonyms: vsp4 antibody, SKD1 antibody, SKD1A antibody, SKD2 antibody, VPS4 antibody, VPS4-1 antibody, zgc:153907 antibody, 4930589C15Rik antibody, AI325971 antibody, AW553189 antibody, vacuolar protein sorting 4 homolog A antibody, vacuolar sorting protein 4 antibody, vacuolar protein sorting 4 homolog A L homeolog antibody, vacuolar protein sorting 4a homolog A (S. cerevisiae) antibody, vacuolar protein sorting 4A antibody, VPS4A antibody, TP03_0351 antibody, vps4a antibody, vps4a.L antibody, Vps4a antibody

Background: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18.

NCBI Accession: NP_037377

UniProt: Q9UN37

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events