UBTD2 antibody

Catalog No. ABIN7244369

Product Details anti-UBTD2 Antibody

Target: UBTD2 (Ubiquitin Domain Containing 2 (UBTD2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBTD2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human UBTD2

Isotype: IgG

Application Details

Application Notes: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBTD2

Target: UBTD2 (Ubiquitin Domain Containing 2 (UBTD2))

Alternative Name: UBTD2 (UBTD2 Products)

Synonyms: zgc:91797 antibody, UBTD2 antibody, DCUBP antibody, 4930571L24 antibody, 9630054F20Rik antibody, AI645720 antibody, RGD1305506 antibody, DC-UbP antibody, ubiquitin domain containing 2 antibody, UBTD2 antibody, ubtd2 antibody, Ubtd2 antibody

Background: UBTD2 (ubiquitin domain containing 2), also known as DCUBP (dendritic cell-derived ubiquitin-like protein), DC-UbP or SB72, is a 234 amino acid cytoplasmic and mitochondrial ubiquitin-like (UbL) protein that contains one C-terminal UbL domain. UbL proteins are involved in a variety of cellular processes, including DNA repair, protein sorting, apoptosis, protein degradation, cell division and autophagy. Predominantly expressed in dendritic cells and detected at high levels in tumor cell lines, UBTD2 has been implicated in apoptosis, cellular differentiation and tumorigenesis. The UbL domain of UBTD2 is 55 % similar and 28.6 % identical to the amino acid sequence of ubiquitin, but it lacks the Gly-Gly motif that is essential for ubiquitination. As its UbL domain does not actively ubiquitinate proteins, UBTD2 is believed to function as a shuttle factor involved in the ubiquitin system.

NCBI Accession: NP_689490

UniProt: Q8WUN7