TXNDC3/NME8 antibody

Catalog No. ABIN7244150

Product Details anti-TXNDC3/NME8 Antibody

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC3/NME8 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Fusion protein of human NME8

Isotype: IgG

Application Details

Application Notes: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TXNDC3/NME8

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Alternative Name: NME8 (TXNDC3 Products)

Synonyms: CILD6 antibody, NM23-H8 antibody, SPTRX2 antibody, TXNDC3 antibody, sptrx-2 antibody, 1700056P15Rik antibody, Sptrx-2 antibody, Txndc3 antibody, Sptrx2 antibody, NME/NM23 family member 8 antibody, NME8 antibody, Nme8 antibody

Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

UniProt: Q8N427

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis