PIG11 antibody, Tp53i11 antibody, Trp53i11 antibody, fi47b03 antibody, si:ch211-122k23.2 antibody, tp53i11 antibody, wu:fi47b03 antibody, zgc:153054 antibody, TP53I11 antibody, trp53i11 antibody, zgc:113403 antibody, tumor protein p53 inducible protein 11 antibody, transformation related protein 53 inducible protein 11 antibody, tumor protein p53 inducible protein 11b antibody, tumor protein p53 inducible protein 11 L homeolog antibody, tumor protein p53 inducible protein 11a antibody, TP53I11 antibody, Trp53i11 antibody, Tp53i11 antibody, tp53i11b antibody, tp53i11.L antibody, tp53i11 antibody, tp53i11a antibody
Background
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome.