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RYR1 antibody
RYR1
Reactivity: Human, Mouse, Rat
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RYR1 Antibody
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Target
See all RYR1 Antibodies
RYR1
(Ryanodine Receptor 1 (Skeletal) (RYR1))
Reactivity
All reactivities for RYR1 antibodies
Human, Mouse, Rat
Host
All hosts for RYR1 antibodies
Rabbit
Clonality
All clonalities for RYR1 antibodies
Polyclonal
Conjugate
All conjugates for RYR1 antibodies
This RYR1 antibody is un-conjugated
Application
All applications for RYR1 antibodies
ELISA, Western Blotting (WB)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human RYR1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB 1:200-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RYR1
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Target
RYR1
(Ryanodine Receptor 1 (Skeletal) (RYR1))
Alternative Name
RYR1 (RYR1 Products )
Synonyms
ryr1 antibody, RYR1 antibody, alphaRYR antibody, CCO antibody, MHS antibody, MHS1 antibody, RYDR antibody, RYR antibody, RYR-1 antibody, SKRR antibody, Ryr1l antibody, CRC antibody, AI528790 antibody, Ryr antibody, skrr antibody, ryanodine receptor 1 antibody, ryanodine receptor 1 (skeletal) antibody, ryanodine receptor 1a (skeletal) antibody, ryanodine receptor 1, skeletal muscle antibody, RYR1 antibody, ryr1a antibody, Ryr1 antibody
Background
This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
Molecular Weight
565 kDa
NCBI Accession
NP_000531
UniProt
P21817
Pathways
Myometrial Relaxation and Contraction , Skeletal Muscle Fiber Development
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