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PPARGC1B antibody
PPARGC1B
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PPARGC1B Antibody
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Target
See all PPARGC1B Antibodies
PPARGC1B
(Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
Reactivity
All reactivities for PPARGC1B antibodies
Human
Host
All hosts for PPARGC1B antibodies
Rabbit
Clonality
All clonalities for PPARGC1B antibodies
Polyclonal
Conjugate
All conjugates for PPARGC1B antibodies
This PPARGC1B antibody is un-conjugated
Application
All applications for PPARGC1B antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human PPARGC1B
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PPARGC1B
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Target
PPARGC1B
(Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
Alternative Name
PPARGC1B (PPARGC1B Products )
Synonyms
PPARGC1B antibody, 4631412G21Rik antibody, Perc antibody, PGC1beta antibody, ERRL1 antibody, PERC antibody, PGC-1(beta) antibody, PGC1B antibody, PPARG coactivator 1 beta antibody, peroxisome proliferative activated receptor, gamma, coactivator 1 beta antibody, PPARGC1B antibody, Ppargc1b antibody
Background
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
NCBI Accession
NP_001166169
UniProt
Q86YN6
Pathways
AMPK Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Lipid Metabolism by PPARalpha
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