MAL antibody

Catalog No. ABIN7243547

Product Details anti-MAL Antibody

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAL antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human MAL

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAL

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Alternative Name: MAL (MAL Products)

Synonyms: AI326936 antibody, Bp50 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, p50 antibody, Mpv17 antibody, Vip17 antibody, mal antibody, wyatt antibody, MALGENE antibody, im:7142606 antibody, zgc:112003 antibody, mal, T-cell differentiation protein antibody, CD40 antigen antibody, myelin and lymphocyte protein, T cell differentiation protein antibody, myelin and lymphocyte protein antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antibody, MAL antibody, Cd40 antibody, Mal antibody, LOC100135389 antibody, mal antibody, tirap.L antibody

Background: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

NCBI Accession: NP_002362

UniProt: P21145

Pathways: Asymmetric Protein Localization