EVC2 antibody

Catalog No. ABIN7243292

Product Details anti-EVC2 Antibody

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EVC2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human EVC2

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EVC2

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Alternative Name: EVC2 (EVC2 Products)

Synonyms: EVC2 antibody, LBN antibody, 1110017L09Rik antibody, Lbn antibody, limbin antibody, EvC ciliary complex subunit 2 antibody, EVC2 antibody, Evc2 antibody

Background: This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants.

Molecular Weight: 148 kDa

NCBI Accession: NP_667338

UniProt: Q86UK5

Pathways: Hedgehog Signaling