Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DEAF1 antibody

DEAF1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7243235
  • Target See all DEAF1 Antibodies
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    Reactivity
    • 52
    • 26
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 62
    • 6
    Rabbit
    Clonality
    • 63
    • 5
    Polyclonal
    Conjugate
    • 27
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DEAF1 antibody is un-conjugated
    Application
    • 57
    • 34
    • 13
    • 6
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human DEAF1
    Isotype
    IgG
    Top Product
    Discover our top product DEAF1 Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    Alternative Name
    DEAF1 (DEAF1 Products)
    Synonyms
    AU042387 antibody, C230009B13Rik antibody, NUDR antibody, SPN antibody, ZMYND5 antibody, MYND5 antibody, spn antibody, DEAF1 antibody, nudr antibody, zmynd5 antibody, CG8567 antibody, DEAF-1 antibody, Deaf-1 antibody, Dmel\\CG8567 antibody, deaf1 antibody, l(3)76BDv antibody, deformed epidermal autoregulatory factor 1 (Drosophila) antibody, DEAF1, transcription factor antibody, DEAF1 transcription factor antibody, deformed epidermal autoregulatory factor 1 homolog antibody, Deformed epidermal autoregulatory factor-1 antibody, Deaf1 antibody, DEAF1 antibody, LOC509260 antibody, deaf1 antibody, deaf-1 antibody
    Background
    Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
    NCBI Accession
    NP_066288
    UniProt
    O75398
    Pathways
    Tube Formation
You are here:
Support