CRHR2 antibody

Catalog No. ABIN7243208

Product Details anti-CRHR2 Antibody

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRHR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human CRHR2

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Alternative Name: CRHR2 (CRHR2 Products)

Synonyms: CRF-RB antibody, CRF2 antibody, CRFR2 antibody, HM-CRF antibody, CRF-R2 antibody, CRFR2alpha antibody, CRFR2beta antibody, Crfr2 antibody, Crf2r antibody, CRH-R2 antibody, crhr2-A antibody, corticotropin releasing hormone receptor 2 antibody, corticotropin releasing hormone receptor 2 S homeolog antibody, CRHR2 antibody, Crhr2 antibody, crhr2.S antibody

Background: The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 48 kDa

NCBI Accession: NP_001189404

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour