Necdin-Like 2 antibody
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- Target See all Necdin-Like 2 (NDNL2) Antibodies
- Necdin-Like 2 (NDNL2)
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Necdin-Like 2 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human NDNL2
- Isotype
- IgG
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- Application Notes
- WB 1:1000-1:5000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.4 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Necdin-Like 2 (NDNL2)
- Alternative Name
- NSMCE3 (NDNL2 Products)
- Synonyms
- mage antibody, zgc:101850 antibody, NDNL2 antibody, HCA4 antibody, MAGEG1 antibody, MAGEL3 antibody, NSE3 antibody, NSMCE3 antibody, 5730494G16Rik antibody, AI642138 antibody, BB044375 antibody, Mageg1 antibody, mage-g1 antibody, NSE3 homolog, SMC5-SMC6 complex component antibody, necdin-like 2 antibody, Nsmce3 antibody, ndnl2 antibody, NDNL2 antibody, NSMCE3 antibody
- Background
- The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
- Molecular Weight
- 34 kDa
- NCBI Accession
- NP_619649
- UniProt
- Q96MG7
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