ARHGEF11 antibody

Catalog No. ABIN7242893

Product Details anti-ARHGEF11 Antibody

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human ARHGEF11

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGEF11

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Alternative Name: ARHGEF11 (ARHGEF11 Products)

Synonyms: ARHGEF11 antibody, GTRAP48 antibody, PDZ-RHOGEF antibody, B930073M02 antibody, E130307F09 antibody, PDZ-RhoGEF antibody, Prg antibody, RhoGEF antibody, mKIAA0380 antibody, Gtrap48 antibody, Rho guanine nucleotide exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor 11 antibody, rho guanine nucleotide exchange factor 11 antibody, arhgef11 antibody, ARHGEF11 antibody, Arhgef11 antibody, LOC511220 antibody

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Molecular Weight: 168 kDa

NCBI Accession: NP_055599

UniProt: O15085

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling