ARHGEF6 antibody

Catalog No. ABIN7242875

Product Details anti-ARHGEF6 Antibody

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human ARHGEF6

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGEF6

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Alternative Name: ARHGEF6 (ARHGEF6 Products)

Synonyms: COOL2 antibody, Cool-2 antibody, MRX46 antibody, PIXA antibody, alpha-PIX antibody, alphaPIX antibody, 1600028C08Rik antibody, 1700038J06Rik antibody, 4930592P22Rik antibody, Rac/Cdc42 guanine nucleotide exchange factor 6 antibody, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody, ARHGEF6 antibody, Arhgef6 antibody

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

NCBI Accession: NP_004831

UniProt: Q15052

Pathways: Neurotrophin Signaling Pathway