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DCC antibody

DCC Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7242482
  • Target See all DCC Antibodies
    DCC (Deleted in Colorectal Carcinoma (DCC))
    Reactivity
    • 47
    • 34
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 56
    • 3
    Rabbit
    Clonality
    • 56
    • 3
    Polyclonal
    Conjugate
    • 25
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DCC antibody is un-conjugated
    Application
    • 44
    • 32
    • 15
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human DCC
    Isotype
    IgG
    Top Product
    Discover our top product DCC Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.7 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DCC (Deleted in Colorectal Carcinoma (DCC))
    Alternative Name
    DCC (DCC Products)
    Synonyms
    CRC18 antibody, CRCR1 antibody, IGDCC1 antibody, MRMV1 antibody, DCC antibody, zdcc antibody, C030036D22Rik antibody, Igdcc1 antibody, xdcc antibody, XDCCa antibody, dcca-A antibody, Dcc antibody, DCC netrin 1 receptor antibody, deleted in colorectal carcinoma antibody, netrin receptor DCC antibody, DCC antibody, dcc antibody, Dcc antibody, LOC100712666 antibody
    Background
    This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
    NCBI Accession
    NP_005206
    UniProt
    P43146
    Pathways
    Regulation of Cell Size
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