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MMP25 antibody

MMP25 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7242293
  • Target See all MMP25 Antibodies
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Reactivity
    • 33
    • 20
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MMP25 antibody is un-conjugated
    Application
    • 18
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human MMP25
    Isotype
    IgG
    Top Product
    Discover our top product MMP25 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Alternative Name
    MMP25 (MMP25 Products)
    Synonyms
    MMP-25 antibody, MMP20 antibody, MMP20A antibody, MMPL1 antibody, MT-MMP 6 antibody, MT-MMP6 antibody, MT6-MMP antibody, MT6MMP antibody, MTMMP6 antibody, F730048C11Rik antibody, Leukolysin antibody, matrix metallopeptidase 25 antibody, MMP25 antibody, Mmp25 antibody
    Background
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
    Molecular Weight
    63 kDa
    NCBI Accession
    NP_071913
    UniProt
    Q9NPA2
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