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MECP2 antibody
MECP2
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MECP2 Antibody
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Target
See all MECP2 Antibodies
MECP2
(Methyl CpG Binding Protein 2 (MECP2))
Reactivity
All reactivities for MECP2 antibodies
Human, Mouse, Rat
Host
All hosts for MECP2 antibodies
Rabbit
Clonality
All clonalities for MECP2 antibodies
Polyclonal
Conjugate
All conjugates for MECP2 antibodies
This MECP2 antibody is un-conjugated
Application
All applications for MECP2 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of human MECP2
Isotype
IgG
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Discover our top product MECP2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:200-1:1000, IHC 1:100-1:300
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MECP2
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Target
MECP2
(Methyl CpG Binding Protein 2 (MECP2))
Alternative Name
MECP2 (MECP2 Products )
Synonyms
AUTSX3 antibody, MRX16 antibody, MRX79 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, 1500041B07Rik antibody, BB130002 antibody, D630021H01Rik antibody, Mbd5 antibody, WBP10 antibody, wu:fk96a04 antibody, zgc:111857 antibody, methyl-CpG binding protein 2 antibody, methyl CpG binding protein 2 antibody, methyl-CpG binding protein 2 S homeolog antibody, MECP2 antibody, Mecp2 antibody, mecp2 antibody, mecp2.S antibody
Background
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development.
Molecular Weight
52 kDa
UniProt
P51608
Pathways
Inositol Metabolic Process , Chromatin Binding , Synaptic Membrane
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