×
For best experience we recommend to activate Javascript in your browser.
TAB3 antibody
TAB3
Reactivity: Human, Mouse
ELISA, WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TAB3 Antibody
(hide)
Target
See all TAB3 Antibodies
TAB3
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
Reactivity
All reactivities for TAB3 antibodies
Human, Mouse
Host
All hosts for TAB3 antibodies
Rabbit
Clonality
All clonalities for TAB3 antibodies
Polyclonal
Conjugate
All conjugates for TAB3 antibodies
This TAB3 antibody is un-conjugated
Application
All applications for TAB3 antibodies
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of human TAB3
Isotype
IgG
Alternatives
(show)
Application Details
(hide)
Application Notes
WB 1:200-1:1000, IHC 1:50-1:200
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TAB3
(hide)
Target
TAB3
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
Alternative Name
TAB3 (TAB3 Products )
Synonyms
MAP3K7IP3 antibody, NAP1 antibody, 4921526G09Rik antibody, Map3k7ip3 antibody, mKIAA4135 antibody, map3k7ip3 antibody, nap1 antibody, tab3 antibody, tab3-a antibody, tab3-b antibody, map3k7ip3l antibody, si:ch211-232d19.8 antibody, si:dkey-30h22.6 antibody, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antibody, TAB3 antibody, Tab3 antibody, tab3.S antibody, tab3 antibody
Background
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Molecular Weight
79 kDa
UniProt
Q8N5C8
Pathways
TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades
Recently viewed
(hide)