DMRT3 antibody

Catalog No. ABIN7241189

Product Details anti-DMRT3 Antibody

Target: DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMRT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human DMRT3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DMRT3

Target: DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))

Alternative Name: DMRT3 (DMRT3 Products)

Synonyms: DMRTA3 antibody, DMRT3 antibody, dmrt3a2 antibody, zDmrt3a-2 antibody, zDmrt3b antibody, dmrt3a1 antibody, zDmart3a antibody, zgc:101766 antibody, doublesex and mab-3 related transcription factor 3 antibody, doublesex and mab-3 related transcription factor 3b antibody, doublesex and mab-3 related transcription factor 3a antibody, DMRT3 antibody, Dmrt3 antibody, dmrt3 antibody, dmrt3b antibody, dmrt3a antibody

Background: The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thought to regulate transcriptional events during early sexual development. The gene encoding DMRT3 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Molecular Weight: 51 kDa

UniProt: Q9NQL9