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DMRT3 antibody

DMRT3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7241189
  • Target See all DMRT3 Antibodies
    DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))
    Reactivity
    • 34
    • 31
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 1
    Rabbit
    Clonality
    • 48
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMRT3 antibody is un-conjugated
    Application
    • 37
    • 21
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human DMRT3
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))
    Alternative Name
    DMRT3 (DMRT3 Products)
    Synonyms
    DMRTA3 antibody, DMRT3 antibody, dmrt3a2 antibody, zDmrt3a-2 antibody, zDmrt3b antibody, dmrt3a1 antibody, zDmart3a antibody, zgc:101766 antibody, doublesex and mab-3 related transcription factor 3 antibody, doublesex and mab-3 related transcription factor 3b antibody, doublesex and mab-3 related transcription factor 3a antibody, DMRT3 antibody, Dmrt3 antibody, dmrt3 antibody, dmrt3b antibody, dmrt3a antibody
    Background
    The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thought to regulate transcriptional events during early sexual development. The gene encoding DMRT3 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
    Molecular Weight
    51 kDa
    UniProt
    Q9NQL9
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