SOCS6 antibody

Catalog No. ABIN7240268

Product Details anti-SOCS6 Antibody

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SOCS6

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Alternative Name: SOCS6 (SOCS6 Products)

Background: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

UniProt: O14544

Pathways: JAK-STAT Signaling, Carbohydrate Homeostasis