SKP1 antibody

Catalog No. ABIN7240244

Product Details anti-SKP1 Antibody

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SKP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SKP1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SKP1

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Alternative Name: SKP1 (SKP1 Products)

Synonyms: EMC19 antibody, OCP-II antibody, OCP2 antibody, SKP1A antibody, TCEB1L antibody, p19A antibody, 15kDa antibody, 2610043E24Rik antibody, 2610206H23Rik antibody, SKP1 antibody, Tceb1l antibody, p19Skp1 antibody, Skp1a antibody, skp1a antibody, zgc:73186 antibody, ocp2 antibody, emc19 antibody, ocp-ii antibody, tceb1l antibody, ARABIDOPSIS SKP1 HOMOLOGUE 1 antibody, ASK1 antibody, ATSKP1 antibody, S phase kinase-associated protein 1 antibody, T4O12.17 antibody, T4O12_17 antibody, UFO INTERACTING PROTEIN 1 antibody, UIP1 antibody, ocp-2 antibody, S-phase kinase associated protein 1 antibody, S-phase kinase-associated protein 1 antibody, S-phase kinase-associated protein 1 pseudogene antibody, S-phase kinase-associated protein 1A antibody, S-phase kinase-associated protein 1 S homeolog antibody, S phase kinase-associated protein 1 antibody, SKP1 antibody, skp1 antibody, LOC100340043 antibody, Skp1a antibody, Skp1 antibody, skp1.S antibody

Background: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Molecular Weight: 19 kDa

UniProt: P63208

Pathways: Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases