GB5 antibody, GBS antibody, Gbeta5 antibody, flr antibody, G protein subunit beta 5 antibody, guanine nucleotide binding protein (G protein), beta 5 antibody, GNB5 antibody, Gnb5 antibody
Background
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist.