DUSP22 antibody

Catalog No. ABIN7239890

Product Details anti-DUSP22 Antibody

Target: DUSP22 (Dual Specificity Phosphatase 22 (DUSP22))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP22 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human DUSP22

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP22

Target: DUSP22 (Dual Specificity Phosphatase 22 (DUSP22))

Alternative Name: DUSP22 (DUSP22 Products)

Synonyms: dusp22 antibody, wu:fa11e09 antibody, zgc:92816 antibody, vhx antibody, jkap antibody, jsp1 antibody, mkpx antibody, DUSP22 antibody, ch73-170d1.1 antibody, zgc:112536 antibody, JKAP antibody, JSP1 antibody, LMWDSP2 antibody, MKPX antibody, VHX antibody, 1110028K04Rik antibody, AW212235 antibody, dual specificity phosphatase 22 antibody, dual specificity phosphatase 22a antibody, dual specificity phosphatase 22b antibody, DUSP22 antibody, dusp22a antibody, dusp22 antibody, dusp22b antibody, Dusp22 antibody

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

UniProt: Q9NRW4