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TNFRSF4 antibody
TNFRSF4
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNFRSF4 Antibody
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Target
See all TNFRSF4 Antibodies
TNFRSF4
(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
Reactivity
All reactivities for TNFRSF4 antibodies
Human
Host
All hosts for TNFRSF4 antibodies
Rabbit
Clonality
All clonalities for TNFRSF4 antibodies
Polyclonal
Conjugate
All conjugates for TNFRSF4 antibodies
This TNFRSF4 antibody is un-conjugated
Application
All applications for TNFRSF4 antibodies
Western Blotting (WB), ELISA
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human TNFRSF4
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB 1:200-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TNFRSF4
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Target
TNFRSF4
(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
Alternative Name
Ox40 (TNFRSF4 Products )
Synonyms
TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Molecular Weight
29 kDa
NCBI Accession
NP_003318
UniProt
P43489
Pathways
Production of Molecular Mediator of Immune Response , Cancer Immune Checkpoints
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