RASA2 antibody

Catalog No. ABIN7239419

Product Details anti-RASA2 Antibody

Target: RASA2 (RAS P21 Protein Activator 2 (RASA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human RASA2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RASA2

Target: RASA2 (RAS P21 Protein Activator 2 (RASA2))

Alternative Name: RASA2 (RASA2 Products)

Synonyms: GAP1M antibody, 5430433H21Rik antibody, AA517451 antibody, AU023900 antibody, GAP1m antibody, RAS p21 protein activator 2 antibody, RASA2 antibody, Rasa2 antibody

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein, a compound suggested to function as a second messenger.

NCBI Accession: NP_006497

UniProt: Q15283