IL-19 antibody

Catalog No. ABIN7239077

Product Details anti-IL-19 Antibody

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-19 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human IL19

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Alternative Name: IL19 (IL19 Products)

Synonyms: IL-10C antibody, MDA1 antibody, NG.1 antibody, ZMDA1 antibody, IL19 antibody, interleukin 19 antibody, IL19 antibody, Il19 antibody

Background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

NCBI Accession: NP_037503

UniProt: Q9UHD0