FAT1 antibody

Catalog No. ABIN7238957

Product Details anti-FAT1 Antibody

Target: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAT1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human FAT1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAT1

Target: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Alternative Name: FAT1 (FAT1 Products)

Synonyms: CDHF7 antibody, CDHR8 antibody, FAT antibody, ME5 antibody, hFat1 antibody, Fath antibody, mFat1 antibody, AU023433 antibody, 2310038E12Rik antibody, FAT1 antibody, FAT atypical cadherin 1 antibody, FAT tumor suppressor homolog 1 (Drosophila) antibody, protocadherin Fat 1 antibody, FAT1 antibody, Fat1 antibody, LOC100175143 antibody, fat1 antibody

Background: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

NCBI Accession: NP_005236

UniProt: Q14517