PFKFB1 antibody

Catalog No. ABIN7238606

Product Details anti-PFKFB1 Antibody

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKFB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human PFKFB1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PFKFB1

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Alternative Name: PFKFB1 (PFKFB1 Products)

Synonyms: zgc:55328 antibody, wu:fi11h10 antibody, PFKFB1 antibody, F6PK antibody, HL2K antibody, PFRX antibody, Pfkfb01 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog antibody, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 antibody, pfkfb1 antibody, PFKFB1 antibody, pfkfb1.S antibody, LOC100475853 antibody, Pfkfb1 antibody

Background: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

NCBI Accession: NP_002616

UniProt: P16118

Pathways: Regulation of Carbohydrate Metabolic Process