PIK3R3 antibody

Catalog No. ABIN7238597

Product Details anti-PIK3R3 Antibody

Target: PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human PIK3R3

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIK3R3

Target: PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

Alternative Name: PIK3R3 (PIK3R3 Products)

Synonyms: AA414954 antibody, p55pik antibody, p55 antibody, p55-GAMMA antibody, pik3r3 antibody, zgc:55564 antibody, zgc:85710 antibody, phosphoinositide-3-kinase regulatory subunit 3 antibody, phosphoinositide-3-kinase, regulatory subunit 3 (gamma) antibody, phosphoinositide-3-kinase, regulatory subunit 3b (gamma) antibody, PIK3R3 antibody, Pik3r3 antibody, pik3r3b antibody

Background: Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3' position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues, predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified, one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.

NCBI Accession: NP_001107644

UniProt: Q92569