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PRKAA1 antibody
PRKAA1
Reactivity: Human, Mouse, Rat
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PRKAA1 Antibody
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Target
See all PRKAA1 Antibodies
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Reactivity
All reactivities for PRKAA1 antibodies
Human, Mouse, Rat
Host
All hosts for PRKAA1 antibodies
Rabbit
Clonality
All clonalities for PRKAA1 antibodies
Polyclonal
Conjugate
All conjugates for PRKAA1 antibodies
This PRKAA1 antibody is un-conjugated
Application
All applications for PRKAA1 antibodies
Immunohistochemistry (IHC), ELISA
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human PRKAA1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:100-1:300
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PRKAA1
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Target
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Alternative Name
AMPK alpha1 (PRKAA1 Products )
Synonyms
AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
Background
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
NCBI Accession
NP_006242
UniProt
Q13131
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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