SLC27A1 antibody

Catalog No. ABIN7238366

Product Details anti-SLC27A1 Antibody

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC27A1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human SLC27A1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC27A1

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Alternative Name: SLC27A1 (FATP1 Products)

Synonyms: ACSVL5 antibody, FATP antibody, FATP1 antibody, Fatp antibody, FATP-1 antibody, FATP-1c antibody, solute carrier family 27 member 1 antibody, solute carrier family 27 (fatty acid transporter), member 1 antibody, SLC27A1 antibody, Slc27a1 antibody

Background: The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.

NCBI Accession: NP_940982

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha