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SCN1A antibody
SCN1A
Reactivity: Human, Rat
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SCN1A Antibody
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Target
See all SCN1A Antibodies
SCN1A
(Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
Reactivity
All reactivities for SCN1A antibodies
Human, Rat
Host
All hosts for SCN1A antibodies
Rabbit
Clonality
All clonalities for SCN1A antibodies
Polyclonal
Conjugate
All conjugates for SCN1A antibodies
This SCN1A antibody is un-conjugated
Application
All applications for SCN1A antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A
Isotype
IgG
Top Product
Discover our top product SCN1A Primary Antibody
Alternatives
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anti-Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A) (AA 465-481), (Intracellular) antibody
SCN1A
Reactivity: Human, Rat, Mouse
IHC, WB, IF, IP, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SCN1A
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Target
SCN1A
(Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
Alternative Name
SCN1A (SCN1A Products )
Synonyms
SCN9A antibody, SCN1A antibody, B230332M13 antibody, Nav1.1 antibody, EIEE6 antibody, FEB3 antibody, FEB3A antibody, FHM3 antibody, GEFSP2 antibody, HBSCI antibody, NAC1 antibody, SCN1 antibody, SMEI antibody, sodium voltage-gated channel alpha subunit 1 antibody, sodium voltage-gated channel alpha subunit 9 antibody, sodium channel, voltage-gated, type I, alpha antibody, SCN1A antibody, SCN9A antibody, Scn1a antibody
Background
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops, each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
NCBI Accession
NP_001159435
UniProt
P35498
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